Prednisone
This medication is used for many different conditions. Generally, it’s used for autoimmune problems, conditions related to swelling, or cancer. Some examples include:
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Allergies or allergic reactions
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Skin conditions
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Conditions affecting certain hormones (e.g., low adrenal hormones)
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Eye conditions
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Lung conditions
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Gut conditions (e.g., ulcerative colitis)
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Conditions related to blood cells
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Certain cancers (e.g., leukemia
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Nervous system conditions (e.g., multiple sclerosis)
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Joint conditions (e.g., rheumatoid arthritis)
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Lupus
How Prednisone works
Prednisone is a corticosteroid. It’s a lab-made medication that’s similar to cortisol, a natural stress hormone your body makes. Prednisone works by calming down your body’s immune response that otherwise would cause you pain and discomfort (e.g., itching, redness, swelling).
What are the side effects of Prednisone?
Common Side Effects
- Swelling (e.g., puffiness in the face, hands, or feet)
- Stomach bloating
- Muscle weakness
- Headache
- Insomnia (trouble sleeping)
- Changes in your mood
- Larger appetite (possibly leading to weight gain)
- Higher blood sugar
Other Side Effects
- Acne
- Higher blood pressure
- Changes in electrolyte levels in the blood (like sodium and potassium)
Serious Side Effects
- Serious allergic reaction: trouble breathing or swallowing; swelling (on your face, lips, mouth, or throat); peeling skin; rash; hives


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